The 2019 Wuhan outbreak of coronavirus disease (COVID-19) has spread worldwide and has been officially declared as a global pandemic. Multiple countries are now experiencing the second wave of the COVID-19 epidemics. Thus, it is gaining a serious concerning momentum to investigate strategies of preventing and dealing with this upsurging second wave at a global level. The epidemic is accelerating rapidly in multiple countries, indicating shortfalls in our preparedness to tackle it. Since multiple countries have imposed travel restrictions, there is a need to model whether earlier implementation of interventions such as social distancing, population behavioural change, and contact tracing are able to contain or mitigate the epidemic or not? While the epidemic is growing exponentially, the entire world health-care system is facing severe burdens, all countries should act and prepare immediately a common agenda to ensure that the health-care system would get the adequate labour, resources, and facilities to vaccinate maximum population and minimise the mortality risk of COVID-19.